type 1 diabetes — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T21729	(±)-Lisofylline		Others
	(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.		Others
TN1403	Arjunolic acid		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
	Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim...		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
T0740	Metformin hydrochloride	Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride	Mitophagy , AMPK , Autophagy
	Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) , a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the proliferation of a variety of Y cells including colon, pro...		Mitophagy , AMPK , Autophagy
T22276	Bis(maltolato)oxovanadium(IV)	BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)	Phosphatase , Others
	Bis(maltolato)oxovanadium(IV) (BMOV) is a potent, reversible, competitive and orally active pan-PTP (protein tyrosine phosphatases)inhibitor with insulin-mimicking effects and anti-diabetic properties. BMOV is a potent i...		Phosphatase , Others
T71394	BMS-823778
	BMS-823778 is an orally available potent and selective inhibitor of 11-β-hydroxysteroid-dehydrogenase 1 (11βHSD-1). BMS-823778 is a potential therapeutic agent for type 2 diabetes mellitus (T2DM).
T19850L	Semaglutide Acetate	Semaglutide Acetate(910463-68-2 Free base)	Glucagon Receptor
	Semaglutide Acetate is an agonist of a glucagon-like peptide 1 (GLP-1) receptor and can be used in studies about the treatment of type 2 diabetes.		Glucagon Receptor
T11408	Orforglipron	LY3502970,GLP-1 receptor agonist 1	Glucagon Receptor
	Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults.		Glucagon Receptor
T40187	GNF2133		DYRK
	GNF2133 is an effective and selective inhibitor of DYRK1A with IC50s of 6.2 nM. GNF2133 can be used in studies about type 1 diabetes.		DYRK
TP1469	Lixisenatide acetate (320367-13-3 free base)	Lixisenatide acetate	Glucagon Receptor
	Lixisenatide acetate is a receptor agonist similar to glucagon-like peptide-1 (glp-1) for the treatment of type 2 diabetes mellitus (T2DM).		Glucagon Receptor
T27439	GS-9667	CVT-3619,CVT 3619	Adenosine Receptor
	GS-9667, a selective and partial agonist of the A(1) adenosine receptor (AR), represents an effective therapy for Type 2 diabetes (T2DM) and dyslipidemia via lowering of free fatty acids (FFA).		Adenosine Receptor
T8511	TM38837		Cannabinoid Receptor
	TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.		Cannabinoid Receptor
TP1796	Albiglutide TFA (782500-75-8 free base)	Albiglutide TFA	Glucagon Receptor
	Albiglutide TFA (782500-75-8 free base) (Albiglutide TFA) is a long acting GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus (T2DM).		Glucagon Receptor
T62512	IHMT-MST1-58		Hippo pathway
	IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity. IHMT-MST1-58 can be used to study type 1 or type 2 diabetes.		Hippo pathway
T76763	Teplizumab	PRV-031,MGA-031	Others
	Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.		Others
T4654	(±)-Ibipinabant	(±)-BMS6462,SLV319,(±)-SLV319	Cannabinoid Receptor
	(±)-Ibipinabant ((±)-SLV319) has been used in trials studying the treatment of Obesity and Obesity and Type 2 Diabetes.		Cannabinoid Receptor
T21694	(R)-Lisofylline	(R)-Lisophylline	STAT
	(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat...		STAT
T24905	TT01001	TT-01001,TT 01001,Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate	Mitochondrial Metabolism
	TT01001 (Ethyl 4-(3-(3,5-dichlorophenyl)thioureido)piperidine-1-carboxylate) is a selective agonist of mitoNEET and reduces oxidative stress injury and neuronal apoptosis by improving mitochondrial dysfunction. TT01001 c...		Mitochondrial Metabolism
T61483	GLP-1R modulator C5		Glucagon Receptor
	GLP-1R modulator C5 is a small molecule GLP-1R orthosteric modulator that enhances GLP-1 binding to GLP-1R via transmembrane sites and can be used in the study of type II diabetes.		Glucagon Receptor
T14283	Amyloid P-IN-1		Beta Amyloid
	amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, and type 2 diabetes mellitus.		Beta Amyloid
T11016	DGAT-1 inhibitor 2		Transferase
	DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) is one of two known DGAT enzymes that catalyze the final step of triglyceride s...		Transferase